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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Idebenone
Research Papers that Mention the Interaction
“Upon idebenone administration, cells deficient in NQO1 show a marked decrease in viability in comparison to NQO1 expressing cells, with idebenone causing ROS production and deleterious effects on ATP levels and cell viability.”
The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina.“ Idebenone increased ATP production and reduced ROS levels, but the effect was partial and cell-specific.”
“In addition, the same dose of idebenone inhibited the increments of lactate and free fatty acid contents and tended to inhibit the decrement of the ATP content in the cerebral cortex of the cerebral ischemic rats.”
Effects of idebenone on the levels of acetylcholine, choline, free fatty acids, and energy metabolites in the brains of rats with cerebral ischemia.
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