supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“ GABA treatment significantly increased ATP levels and NADH dehydrogenase activity in a dose-dependent manner.”
Gamma-Aminobutyric Acid Increases Erythropoietin by Activation of Citrate Cycle and Stimulation of Hypoxia-Inducible Factors Expression in Rats“Currents evoked by simultaneous application of ATP and GABA (I(ATP+GABA)) were significantly smaller compared to the addition of I(ATP) and I(GABA).”
“Another interesting feature is the discovery that ATP is widely found to be a "co-transmitter" at the same synapses in combination with other neurotransmitters such as noradrenaline, acetylcholine, and GABA , altering our picture of the biophysics and biochemistry of neurotransmission at these synapses.”
“ ATP then acts on presynaptic P2X receptors to trigger a prolonged increase in GABA release.”
Cholecystokinin Switches the Plasticity of GABA Synapses in the Dorsomedial Hypothalamus via Astrocytic ATP Release“Data from this study add valuable information suggesting that ATP , via P2X7 activation, not only interferes with the high‐affinity uptake of GABA and Glu but actually favors the release of these amino acids through distinct molecular mechanisms amenable to differential therapeutic control.”
“ ATP (100 μM, for 1 min) caused an inhibition of GABA transport through either GAT‐1 or GAT‐3 transporters, decreasing the Vmax kinetic constant.”
“Combined with the recent findings that GABA depresses taste-evoked ATP secretion [1], the present results indicate that GABA and 5-HT are inhibitory transmitters in mouse taste buds and both likely play an important role in modulating taste responses.”
“ GABA reduces taste-evoked ATP secretion from Receptor cells and is considered to be an inhibitory transmitter in taste buds.”
“The relations between ATP and either Lac, Ch, or GABA levels were exponential.”
“ATP is co‐released with GABA from some inhibitory dorsal horn neurons raising the possibility that ATP could act in concert with GABA to regulate transmitter release from primary afferent terminals if receptors to both transmitters are expressed there.”
“On rat dorsal root ganglion (DRG) nociceptive neurons, inward currents induced by ATP were inhibited after 2 s or 60 s GABA application and unaffected after 10 s application.”
“The effect of SKF-97541 or GABA was observed even after their transient application prior to ATP.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback