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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Adenosine Triphosphate and Galactose

Research Papers that Mention the Interaction

Oxidative stress induced under galactose conditions leads to mitochondrial damage in the form of mitochondrial inner membrane potential dissipation, ATP drop and necrotic cell death, together with increased levels of oxidative modifications in cyclophilin D protein.
Brain : a journal of neurology  •  2012  |  View Paper
Meanwhile, we found that d-gal induced mitochondrial dysfunctions of LECs through increasing reactive oxygen species (ROS), reducing ATP synthesis and mitochondrial potential (MMP), enhancing the concentration of cytoplasm Ca2+ and permeability transition pore (mPTP) opening.
Toxicology letters  •  2018  |  View Paper
Moreover, D-gal administration increased the levels of H2O2 and mitochondrial 3860-bp common deletion, and decreased superoxide dismutase activity and ATP production in the cochlea.
Neurochemistry International  •  2020  |  View Paper
The ATP levels and the membrane potential of the mitochondrial were significantly decreased in the CBM of the D-gal groups compared with the control group.
Biogerontology  •  2020  |  View Paper
ATP ] decreased for at least 10 days during the galactose diet and did not recover, even with resumption of the control diet (50% starch) after 4 or 7 days.
Ophthalmic Research  •  2003  |  View Paper
Incubation of hepatocytes with D-galactosamine GalN ) produced a dose-dependent alteration in cell viability and a fall in ATP and fructose 2,6-bisphosphate (Fru-2,6-P2) levels.
The American journal of physiology  •  1994  |  View Paper
Adenosine triphosphate ATP ) showed a significant decrease in the galactose group compared to the controls from two weeks after beginning of the experiment and the decrease continued.
Nippon Ganka Gakkai zasshi  •  1989  |  View Paper
Serial determination of hepatic metabolites revealed an increase of galactose-1-phosphate levels after oral galactose at 240 and 300 min and a transient decline of ATP at 15 min.
Pediatric Research  •  1988  |  View Paper
Cholestasis produced by bile duct ligation and intraperitoneal injection of D-galactosamine remarkably lowered the Ap4A level to 20% and 42%, respectively; however, the adenosine triphosphate level was only slightly decreased to 65% and 78%, respectively.
Gastroenterology  •  1985  |  View Paper
ATP (0·2 m m ) stimulates galactose transfer and can be replaced by any nucleoside di- or triphosphate except UDP and UTP, which inhibit.
Experimental eye research  •  1978  |  View Paper
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