Possible Interaction: Adenosine Triphosphate and Edetic Acid

“ EDTA potentiated actions of ADP and ATP on endothelial cells by 2.4- and 3.6-fold, respectively.”

“Permeabilization induced by ATP was augmented by chelation of divalent cations with ethylene-diamine-tetraacetic acid and by the addition of lanthanum or cerium (0.01 to 1 mM).”

“Presence of EDTA inhibited conversion of ADP to ATP (prior to luminescence measurement), presumably through a drop in pH caused by the interaction between H 2 EDTA 2− and the Mg 2+ of the pyruvate-kinase system employed.”

“The addition of ATP and Mg ++ together enhanced the inhibition of lactic acid production seen with ATP alone, as did the addition of ATP and EDTA together.”

“The studies reported here demonstrate that ATP may be used in lieu of EDTA to inhibit nuclease digestion of DNA and chromatin.”

“The addition of EDTA to PPi and ATP exhibits more potent inactivation, even though EDTA alone does not inactivate phosphatase.”

“A 'stop solution' containing EDTA was prepared, which greatly retarded plasma ATP degradation by chelating Mg(+2) and Ca(+2) that are co-factors for many ATPases.”

“The V-ATPase inhibitors, suramin, EGTA or EDTA significantly reduced the granular size increase in the presence of ATP.”

“This ecto‐ATPase activity was abolished in the presence of EDTA and was inhibited by 57±11% (n=3) by 200 μM αβ‐MeATP.”

“3 In the presence of EDTA (1 mm), the basal level of inositol trisphosphate (InsP3) was markedly increased and the absolute maximal response to ATP was decreased; however, the response to low concentrations of ATP was enhanced.”