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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Citric Acid
Research Papers that Mention the Interaction
“Other acylcarnitines, lauroylcarnitine (LC) …, tartaric acid (TA) and citric acid (… ATP level and the intracellular pH. From these results, it was considered that one of the action mechanism of acylcarnitines … the intracellular acidosis increases the calcium level through the decrease in ATP levels, followed by opening the tight junction.”
Physiological mechanism for enhancement of paracellular drug transport.“The excessive ATP has a strong inhibitory effect on citric acid accumulation by A. niger.”
Inhibition of oxidative phosphorylation for enhancing citric acid production by Aspergillus niger“The addition of citric acid increased NADH/NAD+ ratio and decreased intracellular ATP level; meanwhile, the activities of pyruvate kinase, citrate synthase and isocitrate dehydrogenase decreased while aspartate aminotransferase activity increased.”
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