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“Regulation is achieved by the concerted action of ATP at conserved nucleotide binding folds and serine phosphorylation at multiple sites by protein kinases A (PKA) and C (PKC).”
The Journal of biological chemistry • 1993 | View Paper
“In the cystic fibrosis transmembrane conductance regulator Cl− channel, this interaction with ATP generates a gating cycle between a closed ( C ) and two open (O1 and O2) conformations.”
Toxicology and applied pharmacology • 1991 | View Paper
“Both C and W forms of citrate synthase are strongly inhibited by ATP , which increases the Km of acetyl-CoA (5-fold at pH 7.5 and 22°) but does not alter the calculated Vmax.”
European journal of biochemistry • 1978 | View Paper
“… C … ATP provides a severe test ftrr enz5'rnatic synthesis: it is endothermic; neither the product (CP) nor AcP has h igh hydro ly t ic … i ty ; ra the enzymat ic reaction is inhibited b1CP at low concentrations;10 the specific activi ty of CK is only moderate.”