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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caseins
Research Papers that Mention the Interaction
“ ATP increased casein lysis by serine proteases, metalloprotease, and pepsin by 20-60% at concentration of 10(-3) M and by 30-260% at 10(-2) M concentration.”
[Effects of biogenic phosphates on protease-induced protein cleavage and functioning of plasminogen activators].“The effects of basic compounds which affected dramatically the phosphorylation of dephosphorylated casein in presence of various ATP concentrations were reported.”
Purification and characterization of casein kinase II from lactating rabbit mammary gland.“After complex formation, hydrolysis of Ub-protein conjugates and also the non-ubiquitinated substrate, casein , was stimulated severalfold by ATP , but non-metabolizable ATP analogs had little or no effect.”
“However, only ATP stimulated casein breakdown and only in the presence of Mg2+.”
“When ubiquitin was removed by ion exchange chromatography, ATP still stimulated breakdown of casein and carbamylated casein twofold.”
“Addition of double-stranded or single-stranded DNA to the protease in the presence of ATP was found to stimulate the hydrolysis of casein or globin 2- to 7-fold, depending on the DNA concentration.”
DNA stimulates ATP-dependent proteolysis and protein-dependent ATPase activity of protease La from Escherichia coli.“Furthermore, ATP hydrolysis is stimulated two- to threefold by polypeptides that are substrates for the protease ( casein , glucagon) but not by nonhydrolyzed polypeptides (insulin, RNase).”
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