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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Adenosine Triphosphate and Carnosine

Research Papers that Mention the Interaction

Cell viability as determined by ATP in cell lysates was reduced only in the presence of carnosine.
PloS one  •  2019  |  View Paper
Carnosine decreased the ATP content through inhibiting both mitochondrial respiration and glycolysis pathways in cultured HeLa cells but not SiHa cells.
Integrative cancer therapies  •  2018  |  View Paper
Here we analyzed whether the anti-neoplastic effect of carnosine , which inhibits glycolytic ATP production, can be antagonized by ATP production via oxidative phosphorylation fueled by pyruvate.
Oncotarget  •  2016  |  View Paper
We observed that 50-100 mM carnosine decreases ATP and ROS concentration and induces cell cycle arrest in G1 phase.
Cancer letters  •  2012  |  View Paper
ResultsIn 48 h single cultures of fibroblasts and tumor cells, 50 and 75 mM carnosine reduced ATP in cell lysates and dehydrogenase activity when compared to the corresponding untreated control cells.
Cancer Cell International  •  2018  |  View Paper