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Last Updated: 3 years ago
supplement:
Benzyl Isothiocyanate
Research Papers that Mention the Interaction
“Furthermore, BITC was found not only to affect ATP production but also to hinder a series of important chemical reactions of the coenzymes involved in the transfer of hydrogen ions in the respiratory chain.”
Antibacterial activity and main action pathway of benzyl isothiocyanate extracted from papaya seeds.“In addition, the BITC treatment resulted in a more rapid depletion of ATP in the rho degrees cells than in the rho(+) cells.”
“The obtained data suggested that the decline in the intracellular ATP level plays an important role in tuning the mode of cell death by BITC.”
“ BITC inhibited inflammasome activation and NLR family, pyrin domain containing 3 (NLRP3)-mediated caspase-1 activation, and decreased the levels of inflammasome activation pro-inflammatory mediators, including mitochondrial reactive oxygen species (ROS) and adenosine triphosphate ( ATP ) secretion in the LPS-stimulated BV2 microglial cells.”
Benzyl isothiocyanate inhibits inflammasome activation in E. coli LPS-stimulated BV2 cells.
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