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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Adenosine and Tolbutamide

supplement:

Adenosine

Research Papers that Mention the Interaction

Tolbutamide 1 mM blocked the inhibitory effect of adenosine on the size of orthodromic population spikes but had no effect on the inhibitory action of adenosine on field EPSPs.
Tolbutamide also blocked the suppression by adenosine of repetitive antidromic spikes induced in calcium-free media with high magnesium but did not prevent the effects of baclofen.
Journal of Neural Transmission  •  1998  |  View Paper
Tolbutamide also counteracted the inhibitory effect of adenosine and, additionally, facilitated the firing rate in some neurons.
The Journal of physiology  •  1995  |  View Paper
Adenosine inhibited insulin secretion stimulated by glucose, glucagon, prostaglandin E2, tolbutamine and theophylline.
The Biochemical journal  •  1977  |  View Paper