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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Adenosine
drug:
Ticlopidine
Research Papers that Mention the Interaction
“ Ticlopidine is an agent that inhibits adenosine diphosphate-induced platelet aggregation.”
Characterization of novel dihydrothienopyridinium and thienopyridinium metabolites of ticlopidine in vitro: role of peroxidases, cytochromes p450, and monoamine oxidases.“The thienopyridine derivative ticlopidine TCL ) is an inhibitor of adenosine diphosphate-induced platelet aggregation.”
“ Ticlopidine is an antiplatelet agent that interferes with platelet membrane function by inhibiting adenosine diphosphate-induced platelet activation.”
“ Ticlopidine , a thienopyridine compound, alters platelet function by inhibiting the binding of adenosine 5 diphosphate to its adenylyl cyclase-coupled receptor site [15, 16].”
“ Ticlopidine administration (250 mg daily) reduced adenosine diphosphate-induced platelet aggregation by 30% without effect on collagen-induced platelet aggregation.”
“ Ticlopidine alone significantly prolonged the mouse tail‐bleeding time and adenosine 5′‐diphosphate‐induced ex vivo platelet aggregation, which was slightly augmented by KGK.”
Pharmacokinetic and pharmacological interactions between ticlopidine hydrochloride and Kangen‐Karyu – Chinese traditional herbal medicine“Thienopyridine compounds, including ticlopidine and clopidogrel, have been found to selectively inhibit adenosine 5 ' diphosphate (ADP)-induced platelet aggregation and adenylyl cyclase ex vivo, but the mechanism of their antiplatelet action remains to be determined.”
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