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Last Updated: 6 months ago

Possible Interaction: Adenosine and Tiazofurin

supplement:

Adenosine

Research Papers that Mention the Interaction

Similar findings were obtained with GTP gamma S. These effects of tiazofurin treatment on guanine nucleotide binding were also associated with decreased adenosine diphosphate-ribosylation of specific G protein substrates by cholera and pertussis toxin.
Blood  •  1990  |  View Paper
The maximal uptake of tiazofurin was 8.29 +/- 0.84% and was shown to be both carrier-mediated, sodium-dependent and inhibited by adenosine which suggests that it uses the carrier for endogenous nucleosides.
Methods and findings in experimental and clinical pharmacology  •  2000  |  View Paper
Introduction … adenosine into the perfusing medium (0.005-0.2 mmol/l) caused similar but more rapid decrease of [3H]-tiazofurin brain clearance (Ki = 6.36 +/- 3.14 x 10(-6) mol/l for nucleus caudate and 11.74 +/- 4.85 x 10(-6) mol/l for cerebral cortex).
Methods and findings in experimental and clinical pharmacology  •  1996  |  View Paper
Mycophenolic acid (MPA) and tiazofurin inhibit inosine-monophosphate dehydrogenase, a’ key-enzyme’ of the purine pathway.
Advances in experimental medicine and biology  •  1994  |  View Paper