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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Adenosine and Threonine

supplement:

Adenosine

supplement:

Threonine

Research Papers that Mention the Interaction

Under basal conditions, adenosine stimulated NO production, eNOS phosphorylation at serine 1177 from 5 minutes to 4 hours and inhibited eNOS phosphorylation at threonine 495 from 5 minutes to 6 hours, but increased phosphorylation of ERK1/2, p38MAPK, and p70S6K only after exposure for 5 minutes.
Journal of cardiovascular pharmacology  •  2017  |  View Paper
Site directed mutation of a key residue in transmembrane domain 4 (TM4) in both CfNT1 and CfAT1 shows that lysine at this position results in a high affinity phenotype, while threonine decreases adenosine affinity in both transporters.
Molecular and biochemical parasitology  •  2013  |  View Paper