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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Adenosine
drug:
Somatostatin
Research Papers that Mention the Interaction
“The importance of adenosine in regulating somatostatin release was shown using adenosine receptor knockout mice.”
Gastrointestinal peptides and regulation of gastric acid secretion“ Adenosine inhibits gastric acid secretion, either directly by acting on acid-secreting parietal cells or indirectly by stimulating the release of the acid inhibitor, somatostatin.”
Regulation of Somatostatin Release by Adenosine in the Mouse Stomach“In isolated perfused glands, somatostatin inhibited the stimulation of secretion produced by VIP, adenosine , and forskolin, as well as by dibutyryl cAMP plus a phosphodiesterase inhibitor.”
“ Somatostatin inhibited insulin release induced by arginine/glucose (A/G), glucagon, glibenclamide, pentoxifyllin, 3',5'-adenosine monophosphate (cAMP), phentolamine, and KCl.”
“Summary 1 × 10 −7 M growth hormone-release inhibiting hormone (GH-RIH or somatostatin ) leads to a 50% inhibition of adenosine 3′,5′-monophosphate (cyclic AMP) accumulation in anterior pituitary tissue during the first 2 min of incubation.”
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