Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Adenosine and Sodium Fluoride

supplement:

Adenosine

Research Papers that Mention the Interaction

Stimulation by adenosine was additive with the effects of GMP-P(NH)P, and alpha- or beta-adrenergic stimulation, but was abolished by prostaglandin E1 or by NaF. Prostaglandin E1 and NaF increased the sensitivity of adenylate cyclase to inhibition by adenosine.
Biochimica et biophysica acta  •  1979  |  View Paper
The hormone-insensitive adenylate cyclase of a Lubrol-PX solubilized membrane preparation stimulated by NaF or 5'-guanylylimido-diphosphate (GppNHp) was also inhibited by adenosine (40% and 90% inhibition at 10"5 M and 10~4 M, respectively).
Circulation research  •  1981  |  View Paper
Theophylline, an inhibitor of phosphodiesterase, caused axons to respond repetitively to stimulation, but this activity had a different pattern from that … and NaF. Imidazole, an activator of phosphodiesterase, impaired neuromuscular transmission and prevented the effects of dibutyryl cAMP and NaF. Adenosine , an inhibitor of protein … to dibutyryl cAMP, NaF ….
The Journal of pharmacology and experimental therapeutics  •  1976  |  View Paper
Adenosine was slightly stimulatory with NaF + AMP, but not with AMP alone.
Archives of biochemistry and biophysics  •  1973  |  View Paper