Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Adenosine and Quinidine





Research Papers that Mention the Interaction

The biphasic response to adenosine was markedly depressed by 10 microg/ml indomethacin and was augmented by combining this agent with quinidine.
Journal of basic and clinical physiology and pharmacology  •  2001  |  View Paper
In contrast, adenosine failed to abolish EADs and TA induced by quinidine (3 microM) or those that occurred spontaneously (i.e., in the absence of drugs).
Circulation research  •  1992  |  View Paper
Quinidine suppressed the action of adenosine in the sinus node (-38 to -52%; P less than 0.05) but not in the ventricle.(ABSTRACT TRUNCATED AT 250 WORDS)
The American journal of physiology  •  1990  |  View Paper
Quinidine , a membrane-stabilizing drug, prolonged the action potential duration, decreased the Vmax, and increased the contractile force, i.e. diminished the electrical and mechanical changes in the atria treated with adenosine.
Archives internationales de pharmacodynamie et de therapie  •  1986  |  View Paper
Though the relaxant effect of adenosine tetraphosphate was blocked in a non-competitive manner by quinidine (5 microM) and phenoxybenzamine (25 microM), theophylline or caffeine (50 microM) failed to block this response.
Archives internationales de pharmacodynamie et de therapie  •  1983  |  View Paper