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Last Updated: 2 years ago

Possible Interaction: Adenosine and Quinacrine

supplement:

Adenosine

Research Papers that Mention the Interaction

Co‐administration of the phospholipase A2 inhibitor quinacrine virtually eliminated adenosine‐induced vasodilatation, yet synergistic interaction between adenosine and pulse perfusion persisted, albeit at a reduced level.
The Journal of physiology  •  1999  |  View Paper
Forskolin (1-300 microM), papaverine (1-100 microM), aminophylline (10-…-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (10-300 microM), quinacrine (1-300 microM) and dibutyryl cyclic AMP (… almost equipotently in both contractile states whereas adenosine (10 microM-1 mM), sodium nitroprusside (10-… (100 microM-3 mM) were virtually ineffective.
European journal of pharmacology  •  1987  |  View Paper
At 50 microM, quinacrine significantly depressed arteriolar reactivity to O2, adenosine , methacholine, and phenylephrine, suggesting nonspecific effects.
The American journal of physiology  •  1986  |  View Paper
The cardiac slowing and atrioventricular block induced by iv injection of adenosine were reduced by the prior administration of quinacrine.
Toxicology and applied pharmacology  •  1972  |  View Paper