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Last Updated: 2 years ago

Possible Interaction: Adenosine and Propranolol

supplement:

Adenosine

Research Papers that Mention the Interaction

Both verapamil and propranolol can exhibit additive effects with adenosine in prolonging AV nodal conduction time; however, only verapamil can reduce the dose of adenosine required to produce AV nodal block.
In conclusion, the negative dromotropic effects of adenosine are preserved and independent even in the presence of verapamil, propranolol , or procainamide.
American heart journal  •  1996  |  View Paper
The effects of epinephrine, histamine, and adenosine were inhibited by the addition of propranolol (a beta-adrenergic antagonist), cimetidine (histamine H2-antagonist), and theophylline (adenosinereceptor antagonist), respectively.
Archives of Dermatological Research  •  2004  |  View Paper
Adenosine significantly lengthened the sinus cycle length in the baseline state (760 ± 165 vs …), during isoproterenol infusion (516 ± 67 vs 766 ± 146 ms, P < 0.05), after propranolol (850 ± 153 vs 914 ± 143 ms, P < 0.05) and after … atropine (662 ± 76 vs 801 ± 121 ms, P < 0.05).
Pacing and clinical electrophysiology : PACE  •  1999  |  View Paper
In the presence of propranolol plus vagotomy, both the negative chronotropic and dromotropic effects of ATP and adenosine were enhanced and attenuated in a similar manner by dipyridamole and aminophylline.
The American journal of cardiology  •  1985  |  View Paper