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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Adenosine and Midazolam

supplement:

Adenosine

Research Papers that Mention the Interaction

Subjects received either 1.5 mg of intravenous midazolam or normal saline placebo 5 min prior to the administration of adenosine.
Emergency medicine  •  2001  |  View Paper
In isolated hearts, midazolam (5, 10, 20 &mgr;M) significantly augmented coronary flow in a concentration-dependent manner in the presence of adenosine (30 nM), an effect reversed by ZM 241385, a selective A2A-receptor antagonist.
Midazolam selectively augments A2A- but not A1-receptor–mediated effects of adenosine by inhibiting nucleoside transporter.
Anesthesiology  •  2000  |  View Paper