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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Adenosine
drug:
Lometrexol
Research Papers that Mention the Interaction
“The inhibition of … growth by DDATHF was effectively prevented by adenosine or deoxyadenosine, whereas guanosine or deoxyguanosine only partially prevented the growth inhibition produced by this folate antimetabolite, implying that the depletion of both ATP and GTP, which occurs with this agent, was responsible for its growth inhibitory effects.”
Evidence for a relationship between intracellular GTP levels and the induction of HL-60 leukemia cell differentiation by 5,10-dideazatetrahydrofolic acid (DDATHF).
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