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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Adenosine
drug:
Kynurenic Acid
Research Papers that Mention the Interaction
“A 2‐h infusion of adenosine increased KYNA levels in a dose‐dependent manner, with 10 mm of adenosine causing a twofold elevation within 1 h. This effect was reversible and was effectively blocked by coinfusion of the specific A1 adenosine receptor antagonist 8‐cyclopentyltheophylline (100 µm).”
“This mechanism may result in a synergism between the neurobiological effects of adenosine and KYNA.”
Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion
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