Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Adenosine and Ketamine

supplement:

Adenosine

Research Papers that Mention the Interaction

The number of subjects who reached VAS 100 within 30 min was significantly lower (P < 0.03) when receiving adenosine + morphine (0/9) and adenosine + ketamine (2/9) than when receiving placebo (7/9).
This may indicate an additive effect on pain reduction when adenosine is given in combination with morphine or ketamine.
Anesthesia and analgesia  •  1994  |  View Paper
In addition, the administration of a sub-effective dose of adenosine produced a synergistic effect with sub-effective doses of MK-801, ketamine and zinc chloride.
Pharmacological reports : PR  •  2012  |  View Paper
Propofol, however, was not effective at inhibition of MC proliferation at doses from 1 to 100 micro M. Ketamine also decreased the cell number at clinically relevant concentrations and increased adenosine 3 prime,5 prime-cyclic monophosphate (cAMP) levels in MC.
Anesthesia and analgesia  •  1997  |  View Paper