Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Adenosine and Isoniazid

supplement:

Adenosine

Research Papers that Mention the Interaction

INH also inhibited both the oxidized nicotinamide adenine dinucleotide (NAD+) and adenosine 5′-monophosphate stimulation of reduced NAD (NADH) oxidase activity associated with the M. phlei and M. tuberculosis H37Ra electron transport particles.
Therefore, INH inhibition of regulation and/or stabilization of the electron transport pathway by NAD+ or adenosine 5′-monophosphate may account, in part, for the lethal action of the drug on mycobacteria.
Antimicrobial Agents and Chemotherapy  •  1977  |  View Paper