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Last Updated: 3 years ago

Possible Interaction: Adenosine and Hypochlorite

supplement:

Adenosine

Research Papers that Mention the Interaction

Preexposure of hearts to the oxidant hypochlorous acid HOCl ) prevented dilatations by ACh, BK, MeATP and Ado (0.1 microM), and the response to Ado (5 microM) was reduced by 68%; postischemic hyperemia was attenuated.
The American journal of physiology  •  1992  |  View Paper
Adenosine and its nucleotides react with hypochlorite to form unstable products that have been identified as the N6 chloramine derivatives.
Free radical research communications  •  1990  |  View Paper
We show that reaction of HOCl with the exocyclic -NH(2) groups of cytidine, adenosine , and guanosine, and the ring NH groups of all bases, yields chloramines (RNHCl/RR'NCl).
Chemical research in toxicology  •  2001  |  View Paper