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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“There was, however, a 9% reduction in the extent (60.6 +/- 4.0 vs 54.9 +/- 4.1, p = 0.03) and a … severity (41.5 +/- 3.2 vs 35.7 +/- 2.9, p = 0.01) of the myocardial perfusion abnormalities seen in patients who received adenosine … heparin compared ….”
“ Heparin caused less attenuation of a challenge with adenosine and probably does not affect mast cell degranulation.”
“Whether heparin modulates bronchial hyperreactivity induced by adenosine , is not well known.”
“ Unfractionated heparin increased adenosine diphosphate-induced expression of P-selectin and GP IIb-IIIa in a dose-dependent manner.”
“The lack of a specific interaction between heparin and PGI2 is supported by the observation that, in the presence of heparin , other prostaglandins such as PGD2 and PGE1 and a non-prostanoid compound such as adenosine also appeared to lose their inhibitory potency.”
Heparin counteracts the antiaggregating effect of prostacyclin by potentiating platelet aggregation.“Aminophylline and heparin may inhibit the responsiveness of airway to adenosine and acetylcholine respectively.”
[Image analysis of airway remodeling and responsiveness in asthmatic guinea pig].
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