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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The Km value calculated for diadenosine tetraphosphate in the presence of Mg2+ is 10 microM … in the presence of Zn2+ 40 microM. Adenosine 5'-tetraphosphate, guanosine 5'-tetraphosphate, and fluoride proved to be inhibitors of the diadenosine tetraphosphate hydrolase; the I50 values were 6, 10, and 20 microM, respectively.”
Human placental (Asymmetrical) diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase: purification to homogeneity and some properties.“ Fluoride potently inhibits diadenosine tetraphosphate hydrolysis in the presence of Mg(2+) (IC(50)=20microM), whereas it is ineffective in the presence of Zn(2+), supporting the view that inhibition involves a specific, MgF(3)(-)-containing transition state analogue complex.”
“After incubation with adenosine and F- ions a distinct decrease of cAMP level was observed in N fractions from the midbrain and thalamus with hypothalamus and in mitochondrial fractions obtained from all the investigated regions.”
“10(-5) M) adenosine inhibits the activation by fluoride practically completely, while at increasing ATP concentrations the inhibition of the fluoride-stimulated activity of adenylate cyclase is decreased.”
[Interrelation of the regulatory effects of adenosine, ATP and fluoride on heart adenylate cyclase].“ Adenosine inhibited basal and fluoride- or hormone-stimulated adenyl cyclase activities from various sources.”
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