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Last Updated: 4 months ago

Possible Interaction: Adenosine and Enprofylline

supplement:

Adenosine

Research Papers that Mention the Interaction

Enprofylline , on the other hand, enhanced the response to exogenous adenosine.
Clinical physiology  •  1995  |  View Paper
In addition, caffeine, but not enprofylline , reduced the cardiovascular response to exogenous adenosine.
Clinical pharmacology and therapeutics  •  1989  |  View Paper
Compared with placebo enprofylline increased heart rate (P less than 0.05) and shifted the heart rate and ventilation dose-response curves of adenosine upwards (P less than 0.05 and P less than 0.02, respectively).
These findings suggest that, with equipotent bronchodilating plasma concentrations, theophylline can inhibit while enprofylline augments some cardio-respiratory stimulant effects of infused adenosine in man.
Acta physiologica Scandinavica  •  1987  |  View Paper
Enprofylline (E) is a xanthine drug that has poor ability to antagonize physiological actions of adenosine.
Journal of applied physiology  •  1987  |  View Paper
It is suggested that the lack of tremorogenic effect of enprofylline is related to its lack of CNS-stimulating behavioural effects and, hence, may reflect its low tendency to antagonize neuro-depressant actions of adenosine.
European journal of respiratory diseases  •  1983  |  View Paper
Theophylline but not enprofylline blocked adenosine inhibition of PMN activation.
The Journal of allergy and clinical immunology  •  1986  |  View Paper
In the presence of theophylline 110 microM the inhibitory effect of adenosine 4 microM was attenuated, whereas the presence of enprofylline 21 microM enforced the inhibitory effect of adenosine.
Acta physiologica Scandinavica  •  1984  |  View Paper
Further in vitro studies revealed that the asthmatic response to adenosine is likely to be mediated via the A(2B) subtype which is selectively antagonised by enprofylline.
British journal of pharmacology  •  2005  |  View Paper
Adenosine uptake was also diminished by certain structural analogues of adenosine (e.g., 2-chloroadenosine), by several alkylxanthine drugs (theophylline, isobutylmethylxanthine, enprofylline and 8-phenyltheophylline), and by certain calcium antagonists (verapamil, nifedipine and trifluoperazine).
Pharmacology  •  1987  |  View Paper
Furthermore, enprofylline is shown to selectively antagonize the stimulatory response, revealing inhibitory effects of compounds such as 2-chloroadenosine and adenosine.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  1986  |  View Paper
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