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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Results of the study suggest that normal therapeutic doses of diltiazem may modulate the metabolism of adenosine and that some of the purine metabolites may be useful markers for specific types of ischemic heart disease.”
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.“ Adenosine , in concentrations achieved in the plasma during myocardial ischemia (0.01-0.1 microM), enhanced the inhibitory effects of nifedipine, verapamil and diltiazem on platelet aggregation 5-100 fold.”
“In addition, the non-dihydropyridine ligand of calcium channels, diltiazem was a weak inhibitor of the accumulation of [3H]adenosine.”
Interactions between calcium channel compounds and adenosine systems in brain of rat“Non-selective group A Ca2+ entry blockers such as diltiazem and verapamil were inactive against adenosine.”
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