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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Adenosine and Creatine

supplement:

Adenosine

supplement:

Creatine

Research Papers that Mention the Interaction

Using electrophysiological recordings and microelectrode biosensors for adenosine, we find that, while having no effect on basal synaptic transmission or paired‐pulse facilitation, pre‐incubation with creatine reduced adenosine release during Mg2+−free/4‐aminopyridine‐induced electrographic seizure activity, whereas RibAde increased adenosine release.
Journal of neurochemistry  •  2018  |  View Paper
In addition, the combined administration of subeffective doses of creatine and adenosine (0.1 mg/kg, ip, nonselective adenosine receptor agonist) or inosine (0.1 mg/kg, ip, nucleoside formed by the breakdown of adenosine) reduced immobility time in the TST.
Purinergic Signalling  •  2015  |  View Paper