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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“However, vasa deferentia from rats treated chronically with clonidine showed lower sensitivity to the inhibitory effects of /%endorphin and adenosine , as well as to those of clonidine (Ishii et al., 1982).”
Adaptation of a neuron to normorphine and clonidine.“On the other hand, adenosine showed potentiation of the submaximal response of clonidine.”
Clonidine — induced behavioural despair in mice: Reversal by antidepressants“Addition of adenosine enhanced the antinociceptive effect of clonidine but not neostigmine.”
“ Adenosine interacted synergistically with neostigmine and additively with clonidine in reducing postoperative hypersensitivity.”
“This stimulus-evoked contraction was also suppressed by adenosine , a P1-purinoceptor agonist, in a concentration-dependent fashion, and the suppression was greatly antagonized by 50 microM clonidine.”
“In addition, the inhibitory effects of N6-phenylisopropyl adenosine, 2'5'-dideoxyadenosine and clonidine on lipolysis and cyclic AMP were enhanced consequent to enzymatic removal of adenosine.”
“ Clonidine inhibits the effect of noradrenaline alone or in combination with adenosine on the cyclic-AMP-generating system.”
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