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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Adenosine
drug:
Carvedilol
Research Papers that Mention the Interaction
“Recently, carvedilol has been reported to reduce oxidative stress, which may consequently reduce the deactivation of adenosine-producing enzymes and increase cardiac adenosine levels.”
β-Adrenoceptor Blocker Carvedilol Provides Cardioprotection via an Adenosine-Dependent Mechanism in Ischemic Canine Hearts“Indeed, we and others have demonstrated that: i) antagonists of either …–aldosterone or β-adrenergic systems enhance NO-dependent pathways; ii) although carvedilol and amlodipine belong to different drug …, both of them can increase cardiac adenosine levels; iii) increased adenosine levels by dipyridamole … associated with the improvement of CHF.”
Cellular mechanisms for the treatment of chronic heart failure: the nitric oxide- and adenosine-dependent pathways
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