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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“ Adenosine 10–5 mol/l shifted the potential of half-maximal activation by –5.9±0.… to –105.3±0.4 mV (n=8; P<0.05), and carbachol 10–5 mol/l by –5.7±0.5 mV from –….9±0.6 mV (n=6; P<0.05).”
Modulation of the hyperpolarization-activated inward current (If) by antiarrhythmic agents in isolated human atrial myocytes“In addition, the antiadrenergic effects of adenosine and carbachol were compared in vitro.”
“ Carbachol inhibited the accumulation of cAMP caused by isoproterenol, adenosine , and prostaglandin E1.”
“ Adenosine has stimulatory effects on the lacrimal gland, and can potentiate the effect of the cholinergic agonist carbachol (Cch).”
Adenosine A2 Receptor Presence and Synergy with Cholinergic Stimulation in Rabbit Lacrimal Gland“ Carbachol combined with either adenosine or CPA increased the secretion 20-fold or more, demonstrating a synergistic effect.”
“Even though adenosine and CPA alone had only a moderate effect on secretion, the observed synergistic effect with carbachol suggests a modulatory role for the adenosine A1 receptor in the lacrimal gland.”
“The anti-adrenergic effect of ADO on I(NaCa) was mimicked by externally applied carbachol (CCh, 10 microM), a muscarinic receptor agonist.”
“ Adenosine at 100 microM depressed depolarisations to the muscarinic agonists carbachol , muscarine and methylfurmethide.”
“2 In lungs from untreated animals, adenosine had little effect unless the perfusion pressure was raised with carbachol (1.1 μm), when it caused a fall in perfusion pressure.”
“4 Adenosine selectively reduced the sensitivity of CA1 neurones to microiontophoretically applied carbachol whereas stable nucleotides did not.”
“ Adenosine , adenosine triphosphate (ATP) and the purine analogues N-ethylcarboxamide adenosine (NECA) and R- and S-phenylisopropyladenosine (PIA) reduced the effects of carbachol on single cell firing and on the population spike.”
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