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Last Updated: 2 years ago

Possible Interaction: Adenosine and Carbachol

supplement:

Adenosine

Research Papers that Mention the Interaction

Adenosine 10–5 mol/l shifted the potential of half-maximal activation by –5.9±0.… to –105.3±0.4 mV (n=8; P<0.05), and carbachol 10–5 mol/l by –5.7±0.5 mV from –….9±0.6 mV (n=6; P<0.05).
Naunyn-Schmiedeberg's Archives of Pharmacology  •  1998  |  View Paper
In addition, the antiadrenergic effects of adenosine and carbachol were compared in vitro.
Journal of the American College of Cardiology  •  1994  |  View Paper
Carbachol inhibited the accumulation of cAMP caused by isoproterenol, adenosine , and prostaglandin E1.
Molecular pharmacology  •  1977  |  View Paper
Adenosine has stimulatory effects on the lacrimal gland, and can potentiate the effect of the cholinergic agonist carbachol (Cch).
Current eye research  •  2010  |  View Paper
Carbachol combined with either adenosine or CPA increased the secretion 20-fold or more, demonstrating a synergistic effect.
Even though adenosine and CPA alone had only a moderate effect on secretion, the observed synergistic effect with carbachol suggests a modulatory role for the adenosine A1 receptor in the lacrimal gland.
Experimental eye research  •  2008  |  View Paper
The anti-adrenergic effect of ADO on I(NaCa) was mimicked by externally applied carbachol (CCh, 10 microM), a muscarinic receptor agonist.
Cell calcium  •  2001  |  View Paper
Adenosine at 100 microM depressed depolarisations to the muscarinic agonists carbachol , muscarine and methylfurmethide.
General pharmacology  •  1995  |  View Paper
2 In lungs from untreated animals, adenosine had little effect unless the perfusion pressure was raised with carbachol (1.1 μm), when it caused a fall in perfusion pressure.
British journal of pharmacology  •  1992  |  View Paper
4 Adenosine selectively reduced the sensitivity of CA1 neurones to microiontophoretically applied carbachol whereas stable nucleotides did not.
British journal of pharmacology  •  1989  |  View Paper
Adenosine , adenosine triphosphate (ATP) and the purine analogues N-ethylcarboxamide adenosine (NECA) and R- and S-phenylisopropyladenosine (PIA) reduced the effects of carbachol on single cell firing and on the population spike.
Brain Research  •  1988  |  View Paper
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