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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Adenosine
supplement:
Cannabidiol
Research Papers that Mention the Interaction
“ CBD has been shown to modulate a wide variety of targets including the cannabinoid receptors, orphan GPCRs such as GPR55 and GPR18, serotonin, adenosine , and opioid receptors as well as ligand-gated ion channels among others.”
Synthetic and Natural Derivatives of Cannabidiol.“Here, we report that intrahypothalamic injection of CBD (10μg/1μL) increases the extracellular levels of AD collected from nucleus accumbens.”
“These preliminary findings suggest that CBD promotes the endogenous accumulation of AD.”
Intrahypothalamic injection of cannabidiol increases the extracellular levels of adenosine in nucleus accumbens in rats“ CBD and, less potently, THC decreased uptake of [3H]adenosine to a similar extent as [3H]thymidine in both murine microglia and RAW264.7 macrophages.”
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