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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Adenosine and Calcium Channel Blockers

Research Papers that Mention the Interaction

The conversion rates for the calcium channel blockers (98%) were statistically higher than the adenosine group (86.5%), p=0.002, RR 1.13, 95% CI 1.04-1.23.
Resuscitation  •  2009  |  View Paper
In the calcium channel blocker responders, the combination of adenosine and calcium blocker reduced pulmonary vascular resistance by 49%, increased stroke volume by 33% and decreased mean pulmonary artery pressure by 14% compared with drug-free baseline values.
Journal of the American College of Cardiology  •  1993  |  View Paper
Finally a cellular model was approached to clarify a possible interference of calcium entry blocker with adenosine a t the membrane receptor level.
Annals of the New York Academy of Sciences  •  1988  |  View Paper
2 Nifedipine and Bay K 8644, a calcium channel antagonist and activator respectively, enhanced the inhibitory action of adenosine in a concentration‐dependent manner.
British journal of pharmacology  •  1990  |  View Paper
It is concluded that calcium antagonists may, through intercalation with the sarcolemmal membrane, inhibit efflux of adenosine formed by catabolism of adenine nucleotides in ischaemic myocytes.
Cardiovascular research  •  1986  |  View Paper