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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Antioxidant properties of salicylates, adenosine release induced by sodium salicylate and aspirin-triggered lipoxin formation are additional mechanisms that may contribute to anti-inflammatory properties of aspirin and/or sodium salicylate.”
Anti-inflammatory effects of aspirin and sodium salicylate.“While aspirin has been suggested to mediate adenosine action , the roles of adenosine and its receptors in aspirin-intolerant asthma (AIA) are not well-defined.”
“The serum factor responsible …; (2) pretreatment with aspirin … adenosine diphosphate-induced expression of this factor in platelet-rich plasma; (3) the CR-inducing factor was also contained in supernatants … activity of serum and platelet supernatants was inhibited by incubation with antibody against PDGF but not by antibody against C5.”
“ Aspirin and sodium salicylate dramatically increased concentrations of adenosine in exudates, a property shared with methotrexate and sulfasalazine.”
“These include inhibition of NFkappaB translocation to the nucleus and the capacity of aspirin to promote accumulation of adenosine , a potent antiinflammatory autocoid.”
Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFkappaB knockout mice.
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