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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Adenosine and Aprotinin

supplement:

Adenosine

Research Papers that Mention the Interaction

Aprotinin and tranexamic acid both mitigated the early postoperative reduction of adenosine diphosphate-induced platelet aggregation seen in the controls (p < 0.05).
The Journal of thoracic and cardiovascular surgery  •  1994  |  View Paper
Aprotinin inhibited adenosine diphosphate-induced platelet aggregation, but it exhibited no effect on the expression of GP IIIa and P-selectin.
Anesthesia and analgesia  •  2000  |  View Paper
Both types of aprotinin significantly increased vasorelaxation to adenosine when compared with controls, but did not affect that to sodium nitroprusside.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery  •  2007  |  View Paper
Diltiazem appears to be less effective in preventing calcium overload during ischemia-reperfusion, and protease inhibition with aprotinin (150 KIU/ml) seems to be highly effective in suppressing lysosomal enzyme activation-release and maintaining myocardial adenosine diphosphate and adenosine monophosphate levels.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation  •  1992  |  View Paper