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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Adenosine
drug:
Aminopterin
Research Papers that Mention the Interaction
“In tumor tissue, aminopterin reduced the ATP level by nearly 50% and, when used concurrently with adenylic acid , by nearly 70%.”
Effect of Aminopterin and Certain Purine Antagonists on Adenine Nucleotide Levels in Tissues of Tumor-Bearing Mice.∗“In addition, methotrexate and aminopterin , which affect thymine levels by inhibiting dihydrofolate reductase, also up-regulate UMPSase in N. plumbaginifolia cells.”
Uridine 5'-Monophosphate Synthase Is Transcriptionally Regulated by Pyrimidine Levels in Nicotiana plumbaginifolia
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