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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Adenosine and Amifampridine

supplement:

Adenosine

Research Papers that Mention the Interaction

To test whether a conductance increase to potassium … mediated adenosine action, the K-channel blockers, 3,4-diaminopyridine (1-100 mumol/l) or 4-aminopyridine (100-500 mumol/l) were … or Cs partially substituted for K. These substances reduced or prevented adenosine from having its depressant … on synaptic transmission.
When the increased excitability was counteracted by high Mg or low concentrations of tetrodotoxin, 3,4-diaminopyridine still blocked adenosine action.
Neuroscience  •  1988  |  View Paper