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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Adenosine and Alpha Adrenergic Agent

Research Papers that Mention the Interaction

These results suggest that adenosine , acting via A1 receptors, modulates alpha 1-adrenergic effects on thermogenesis in brown fat cells, an action that is analogous to its inhibition of beta-adrenergic receptor-stimulated thermogenesis.
Molecular pharmacology  •  1987  |  View Paper
A recently reported study in isolated guinea pig and rat hearts suggested that adenosine causes coronary vasodilation by inhibition of alpha adrenergic activity in the coronary resistance vessels and that the effect can be competitively blocked by alpha adrenergic blockade (4).
Since myocardial reactive hyperemia has been shown to be unaffected by alpha adrenergic blockade (5), confirmation of inhibition of adenosine induced coronary vasodilation by alpha adrenergic blocking agents would negate its proposed role in the reactive hyperemia response.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1973  |  View Paper