Possible Interaction: Adenosine and Alanine

“In chicken liver homogenate gluconeogenesis from precursors such as alanine , glutamate, glutamine and aspartate, which are not converted into glucose by the perfused chicken liver, proceeded at rates equal to or higher than that with lactate, being markedly inhibited by Ado.”

“The suppression by pyruvate and L-alanine was strongly reduced by 1 X 10(-4) M adenosine.”

“However, the specific activity of liver glycogen found in animals receiving adenosine or adenosine pluscortisol and radioactive glucose or alanine is higher than that observed in animals injected with saline or cortisol.”

“Most of spores of B. anthracis introduced into the peritoneal cavity of rats could germinate when 5 mg of L-alanine and 5 mg of adenosine were injected by the same route shortly before the spore injection.”

“The calcium requirement itself was remarkably diminished under the condition in which l‐alanine and a certain purine nucleoside analog, adenosine or inosine, coexisted.”

“Pulvertaft and Haynes (1951) reported that although 14 amino acids in an arbitrary mixture, DL-alanine , L-tyrosine, DL-cystine, DL-tryptophan, and methionine did not have stimulative effect on the germination of Bacilus subtilis, they did stimulate spore germination when adenosine was added.”