supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Adenosine
Research Papers that Mention the Interaction
“In that this translocation has been previously associated with the antiadrenergic property of A1R, it is apparent that the interactive effects of adenosine and β1‐adrenergic agonists on function are complex in the heart.”
Crosstalk between adenosine A1 and β1‐adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes“ Adenosine elicited antiadrenergic action on both beta(1)- and beta(2)-adrenergic signaling cascades by reducing the phosphorylation status of phospholamban.”
“Irrespective of cell type and species, adenosine inhibits membrane currents that are stimulated by β‐adrenergic agonists and other agents known to stimulate the activity of the enzyme adenylyl cyclase.”
“CONCLUSIONS Ad nosine si gnificantly increases transthoracic and transmyocardial DFT, effects that are mediated by the A1 adenosine myocardial receptor through an ant iadrenergic me chanism.”
“These results suggest that the elevated interstitial level of adenosine exerts a greater antiadrenergic effect in the aged heart, rendering it less responsive to beta-adrenergic stimulation.”
“ Adenosine and acetylcholine exert negative chronotropic and anti-adrenergic effects on nonischemic myocardium presumably via receptor coupling to the same or similar inhibitory guanine nucleotide binding protein (Gi).”
“In addition, adenosine was found to potentiate the α1‐adrenergic production of inositol phosphates in astrocytes.”
Synergistic Regulation of Cytosolic Ca2+ Concentration by Adenosine and α1‐Adrenergic Agonists in Mouse Striatal Astrocytes
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback