supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“As with abacavir, acyclovir showed a dose dependent increase in affinity for peptides with valine and isoleucine at their C-terminus.”
Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity“If peptides are protected from luminal proteolysis by fatty acylation, or if a nonpeptide drug, acyclovir , is esterified with valine to enhance bioavailability, the peptides nevertheless are absorbed by peptide transporters.”
“It has been reported that conjugating acyclovir , a potent antiviral with low oral bioavailability, to L-valine increases its urinary excretion in rats.”
“Only the mucosal-to-serosal transport of acyclovir was increased by conjugation with L-valine (approximately 7-fold), suggesting the involvement of a carrier-mediated mechanism.”
“If peptides are protected from luminal proteolysis by fatty acylation, or if a nonpeptide drug, acyclovir , is esterified with valine to enhance bioavailability, the peptides nevertheless are absorbed by peptide transporters.”
Nutrient absorption.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback