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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acyclovir
supplement:
Carrageenan
Research Papers that Mention the Interaction
“In the in vitro release experiment, carrageenan significantly decreased the release rate of acyclovir , retarded the dissolution of poloxamer 407 and slowed the gel erosion (weight loss) in a concentration-dependent manner.”
“In vivo local drug residence experiment indicated that carrageenan significantly prolonged local residence of acyclovir and further showed a synergistic bioadhesive effect with acrylic acid polymers (Carbopol).”
Effect of carrageenan on poloxamer-based in situ gel for vaginal use: Improved in vitro and in vivo sustained-release properties.
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