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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylglucosamine and Penicillins

Research Papers that Mention the Interaction

Penicillin inhibits the incorporation of D- and L-alanine N-acetylglucosamine at concentrations in excess of 10 mug of penicillin per ml; however, minicells are insensitive to penicillin-induced lysis.
Journal of bacteriology  •  1977  |  View Paper
Rather unexpectedly, penicillin also inhibited markedly, though incompletely, the incorporation of GlcNAc and of MurNAc-pentapeptide into the preexisting peptidoglycan.
Annals of the New York Academy of Sciences  •  1974  |  View Paper
Penicillin not only strongly inhibits release of D-alanine (98% at 1 mug/ml), but also markedly inhibits incorporation of acetylglucosamine and N-acetylmuramic acid-pentapeptide into the preformed cell-wall peptidoglycan.
Proceedings of the National Academy of Sciences of the United States of America  •  1972  |  View Paper