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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylglucosamine
supplement:
Ovalbumin
Research Papers that Mention the Interaction
“In addition, N-OVA decreased the antigenicity of OVA 1000-fold.”
Changes in the antigenicity and allergenicity of ovalbumin in chicken egg white by N-acetylglucosaminidase.“In vitro uptake of OVA in cultured EC was saturable and inhibited by mannan, mannose, fructose, N-acetylglucosamine , EDTA or monensin, but not by galactose or AOM.”
Receptor-mediated endocytosis of ovalbumin by two carbohydrate-specific receptors in rat liver cells. The intracellular transport of ovalbumin to lysosomes is faster in liver endothelial cells than in parenchymal cells.“Inhibition patterns with N-acetylglucosamine or UDP-glucose as inhibitors of the galactosylation of ovalbumin indicated that either UDP-galactose or N-acetylglucosamine can bind to an enzyme-Mn2+ complex by a random equilibrium mechanism.”
“These results indicate that cleavage of the terminal carbohydrate, and particularly N-acetylglucosamine , reduces the allergenicity of OA.”
Cleavage of the terminal N-acetylglucosamine of egg-white ovalbumin N-glycans significantly reduces IgE production and Th2 cytokine secretion.
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