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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Acetylglucosamine and Hyaluronan



Research Papers that Mention the Interaction

In parallel with the opposing actions of these aminosugars on glucose transport, GlcN inhibits hyaluronan and SGAG synthesis while GlcNAc stimulates hyaluronan synthesis.
Osteoarthritis and cartilage  •  2009  |  View Paper
The results showed that NAG promoted HA production while had no effect on the expression of HA-synthesizing enzymes 1, 2 and 3 mRNA in human dermal fibroblasts.
Archives of Dermatological Research  •  2009  |  View Paper
In contrast to isosmotic concentrations of glucose, NAG increases the synthesis of hyaluronan by mesothelial cells and fibroblasts in a dose-dependent manner.
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis  •  1998  |  View Paper
In the presence of NAG, these parameters were comparable with the control group, but at the same time NAG stimulated synthesis of hyaluronan : +116% versus control, P < 0.001 and + 96% versus GLU, P < 0.01.
Translational research : the journal of laboratory and clinical medicine  •  2007  |  View Paper
Taken together, our findings suggest that NAG is a new modulator of HA synthesis.
We found that N-acetylglucosamine (NAG) increased the production of HA by cultured keratinocytes dose dependently, but had no effect on the production by skin fibroblasts.
Skin Pharmacology and Physiology  •  2004  |  View Paper