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Possible Interaction: Acetylglucosamine and Glucosamine

supplement:

Glucosamine

Research Papers that Mention the Interaction

These findings suggest that glucosamine may inhibit growth of ALVA41 cancer cells through downregulation of PA28γ and inhibition of proteasomal activity via O-GlcNAc modification.
We further demonstrated that inhibition of O-GlcNAc abrogated PA28γ suppression induced by glucosamine.
Experimental & Molecular Medicine  •  2011  |  View Paper
Increasing O-GlcNAc levels, using glucosamine or PUGNAc, enhanced ubiquitination.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  •  2008  |  View Paper
These observations suggest that glucosamine modulates endothelial cell activation possibly via O-GlcNAc modification, and may exhibit an anti-inflammatory action on atherosclerosis.
International journal of molecular medicine  •  1998  |  View Paper
Substrate and inhibitor studies further revealed that leukaemic cell hexosaminidases hydrolyse galactopyranosides at significantly lower rates than glucopyranosides and that the hydrolysis of N-acetyl beta-D glucosamine is inhibited by both glucosamine and galactosamine products.
Leukemia research  •  1987  |  View Paper
Glucosamine treatment, which bypasses the rate-limiting step in the synthesis of substrate for glycosylation, increased both O-GlcNAc and leptin, whereas inhibition of O-glycosyltransferase (OGT) decreased O-GlcNAc and leptin.
The Journal of biological chemistry  •  2019  |  View Paper
Results:The two glucosamines showed opposite effects in monolayer culture: GlcN·HCl significantly reduced proliferation and GlcNAc significantly augmented cellular metabolism.
Tissue Engineering and Regenerative Medicine  •  2018  |  View Paper
However, the results indicated that the titer of GlcN and GlcNAc decreased significantly due to the transportation of GlcN and GlcNAc from the culture broth to the inside of cells.
Sheng wu gong cheng xue bao = Chinese journal of biotechnology  •  2012  |  View Paper
Glucose, mannose, fructose, and glucosamine strongly inhibited the transport of these amino-acetylated sugars and GlcNAc and ManNAc strongly affected ManNAc and GlcNAc uptake, respectively.
FEBS letters  •  2002  |  View Paper
Glucokinase activities that … glucose and glucosamine are … by N-acetyl-glucosamine and xylose, were found to be present in the non-sulphur photosynthetic bacteria Rhodospirillum rubrum, the blue-green algae Anacystis montana, and the protists Chlorella pyrenoidosa and Chlamydomonas reinhardtii (green algae), Hypochytrium catenoides (Hypochytridiomycete) and Saprolegnia Iitoralis (Oomycete).
Bio Systems  •  1978  |  View Paper
Glucosamine and N-phenylacetylglucosamine were definitely inhibitory to growth at the concentrations studied.
Canadian journal of microbiology  •  1976  |  View Paper
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