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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylglucosamine
drug:
Gentamicin
Research Papers that Mention the Interaction
“Mean urinary concentration of N-acetyl glucosaminidase and alanine aminopeptidase increased faster and to higher levels with gentamicin than with tobramycin.”
Renal toxicity during therapy with gentamicin or tobramycin.“Cells exposed to 2 mM gentamicin for 6 days displayed a significant decrease in specific activities of leucine aminopeptidase, NaK ATPase, and N-acetyl glucosaminidase , and an increase in total cellular phospholipids (P < .05).”
HWA-448 reduces gentamicin toxicity in LLC-PK1 cells.“This indicates that gentamicin may induce an altered carbohydrate metabolism resulting in a decrease of N-acetyl-glucosamine , mannose, galactose and glucose in the glycocalyx lining the epithelial cells as well as in the gelatinous layer of the otolithic membrane or cupula in the vestibular end organs.”
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