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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylglucosamine
supplement:
Galactose
Research Papers that Mention the Interaction
“Poly-N-acetyllactosamine chains are synthesized by repeated alternating additions of N-acetylglucosamine and galactose , catalyzed by beta-1,3-N-acetylglucosaminyltransferases (poly-N-acetyllactosamine synthase) and beta-1,4-galactosyltransferases.”
Why are glycoproteins modified by poly-N-acetyllactosamine glyco-conjugates?“The relationship between exposed galactose and N‐acetylglucosamine on IgG in RA, JCA and SS was investigated.”
“Lactose as well as oligosaccharides in which galactose is linked beta 1----3 or beta 1----4 to N-acetylglucosamine are less efficient acceptors.”
“These mutants failed to grow on galactose and also showed lower growth rate in presence of GlcNAc.”
Upregulation of galactose metabolic pathway by N-acetylglucosamine induced endogenous synthesis of galactose in Candida albicans.“N-acetylglucosaminidase induction in cells grown on N-acetylglucosamine was also repressed by fructose, mannose or galactose , although to a lesser extent than by glucose, and sucrose repressed enzyme production by only 10%.”
“ N-Acetyl-D-glucosamine inhibited the enzyme competitively (Ki = 4.3 x 10(-4) M), whereas N-acetyl-D-galactosamine did not; in contrast, D-glucosamine and D-galactosamine activated it.”
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