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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Urethane
Research Papers that Mention the Interaction
“ NAC markedly inhibited the induction of lung tumors in mice by a potent carcinogen ( urethane).”
Metabolic, desmutagenic and anticarcinogenic effects of N-acetylcysteine.“In addition, NAC prevented the clastogenic and toxic effects resulting from the interaction of Se with urethane.”
“While NAC produced a significant inhibition, Se further enhanced urethane clastogenicity.”
Interactions between N–acetylcysteine and sodium selenite in modulating the clastogenicity of urethane and 2–acetylaminofluorene in mice“In general, NAC and NACAT have a moderate chemopreventive effect on lung tumorigenesis induced by urethane in mice.”
“In mice treated with three different doses of urethan and fed NAC in the diet, a significant reduction in lung tumor multiplicity was found only at one dose level.”
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